Gene_EntrezGene:3156 Gene_EntrezGene:51706 Gene_EntrezGene:3157 Gene_EntrezGene:1717 Gene_EntrezGene:11161 Gene_EntrezGene:1718 Gene_EntrezGene:4047 Gene_EntrezGene:2224 # _database biomine v3_21_01 sr3-9.cs.helsinki.fi http://biomine.cs.helsinki.fi/bm/links.cgi # _canvas 0.0,0.0,2944.4,2054.4 ActiveSite_InterPro:IPR000590 BiologicalProcess_GO:GO:0008299 participates_in best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=InterPro source_db_version=22.0 Family_InterPro:IPR010122 ActiveSite_InterPro:IPR000590 -is_part_of best=0 goodness=0.8 rarity=1 relevance=0.8 reliability=1 source_db_name=InterPro source_db_version=22.0 MolecularFunction_GO:GO:0004421 ActiveSite_InterPro:IPR000590 -has best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=InterPro source_db_version=22.0 BiologicalProcess_GO:GO:0010142 BiologicalProcess_GO:GO:0045337 is_a best=0 goodness=0.8 rarity=1 relevance=0.8 reliability=1 source_db_name=GO source_db_version=2009-08-31_19:30 Gene_EntrezGene:3156 Drug_KEGG:D00359 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D00359 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D00434 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Drug_KEGG:D00434 Pathway_KEGG:hsa00100 targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D00887 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D00887 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D00889 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D00889 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D00892 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D00892 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D00893 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D00893 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D01862 -targets best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Drug_KEGG:D01862 Pathway_KEGG:hsa00100 targets best=1 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D01915 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D01915 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D02258 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D02258 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D03601 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D03601 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D03643 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D03643 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D03816 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D03816 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D07474 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D07474 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D08410 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D08410 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Drug_KEGG:D08492 -targets best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Pathway_KEGG:hsa00100 Drug_KEGG:D08492 -targets best=0 goodness=0.714201 rarity=0.7936 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Protein_UniProt:P04035 Enzyme_EC:1.1.1.34 -subsumes best=0 goodness=0.77164 rarity=0.8123 relevance=0.95 reliability=1 source_db_name=SwissProt source_db_version=57.6 Enzyme_EC:1.1.1.34 Protein_UniProt:P51639 subsumes best=0 goodness=0.77164 rarity=0.8123 relevance=0.95 reliability=1 source_db_name=SwissProt source_db_version=57.6 BiologicalProcess_GO:GO:0008299 Family_InterPro:IPR010122 -participates_in best=0 goodness=0.68272 rarity=0.7586 relevance=0.9 reliability=1 source_db_name=InterPro source_db_version=22.0 Family_InterPro:IPR010122 MolecularFunction_GO:GO:0004421 has best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=InterPro source_db_version=22.0 BiologicalProcess_GO:GO:0016126 Gene_EntrezGene:11161 -participates_in best=1 evidence_code=IEA goodness=0.574715 rarity=0.6386 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:11161 Protein_UniProt:Q9UKR5 codes_for best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 BiologicalProcess_GO:GO:0006695 Gene_EntrezGene:1717 -participates_in best=1 evidence_code=IMP goodness=0.539624 rarity=0.5996 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Pathway_KEGG:hsa00100 Gene_EntrezGene:1717 -participates_in best=1 goodness=0.612798 rarity=0.766 relevance=0.8 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:1717 Protein_UniProt:Q9UBM7 codes_for best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 BiologicalProcess_GO:GO:0006695 Gene_EntrezGene:1718 -participates_in best=1 evidence_code=NAS goodness=0.539624 rarity=0.5996 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:1718 Pathway_KEGG:hsa00100 participates_in best=1 goodness=0.612798 rarity=0.766 relevance=0.8 reliability=1 source_db_name=KEGG source_db_version=51 Protein_UniProt:Q15392 Gene_EntrezGene:1718 -codes_for best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 BiologicalProcess_GO:GO:0006695 Gene_EntrezGene:2224 -participates_in best=0 evidence_code=TAS goodness=0.539624 rarity=0.5996 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 BiologicalProcess_GO:GO:0008299 Gene_EntrezGene:2224 -participates_in best=1 evidence_code=IEA goodness=0.540544 rarity=0.6006 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:3157 Gene_EntrezGene:2224 -refers_to best=0 goodness=0.3 rarity=1 relevance=0.3 reliability=1 source_db_name=MIM source_db_version=2009-09-01 Gene_EntrezGene:2224 Gene_EntrezGene:36209 is_homologous_to best=0 goodness=0.716767 hom_AA=0.469027 hom_NT=0.544739 rarity=0.896 relevance=0.8 reliability=1 source_db_name=HomoloGene source_db_version=64 Pathway_KEGG:hsa00100 Gene_EntrezGene:2224 -participates_in best=1 goodness=0.612798 rarity=0.766 relevance=0.8 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:2224 Protein_UniProt:P14324 codes_for best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Enzyme_EC:1.1.1.34 Gene_EntrezGene:25675 -codes_for best=0 goodness=0.687891 rarity=0.7643 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:25675 Gene_EntrezGene:3156 is_homologous_to best=0 goodness=0.69644 hom_AA=0.928974 hom_NT=0.862082 rarity=0.8706 relevance=0.8 reliability=1 source_db_name=HomoloGene source_db_version=64 Gene_EntrezGene:25675 Protein_UniProt:P51639 codes_for best=0 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:3156 BiologicalProcess_GO:GO:0006695 participates_in best=0 evidence_code=IEA goodness=0.539624 rarity=0.5996 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:3156 BiologicalProcess_GO:GO:0008299 participates_in best=0 evidence_code=IEA goodness=0.540544 rarity=0.6006 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:3156 Enzyme_EC:1.1.1.34 codes_for best=0 goodness=0.687891 rarity=0.7643 relevance=0.9 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Pathway_KEGG:hsa00100 participates_in best=0 goodness=0.612798 rarity=0.766 relevance=0.8 reliability=1 source_db_name=KEGG source_db_version=51 Gene_EntrezGene:3156 Protein_UniProt:P04035 codes_for best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:3157 BiologicalProcess_GO:GO:0006695 participates_in best=1 evidence_code=IEA goodness=0.539624 rarity=0.5996 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 BiologicalProcess_GO:GO:0008299 Gene_EntrezGene:3157 -participates_in best=0 evidence_code=IEA goodness=0.540544 rarity=0.6006 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:3157 MolecularFunction_GO:GO:0004421 has best=1 evidence_code=TAS goodness=0.701248 rarity=0.7792 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Protein_UniProt:Q01581 Gene_EntrezGene:3157 -codes_for best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 BiologicalProcess_GO:GO:0045337 Gene_EntrezGene:36209 -participates_in best=0 evidence_code=IC goodness=0.806363 rarity=0.896 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 BiologicalProcess_GO:GO:0006695 Gene_EntrezGene:4047 -participates_in best=1 evidence_code=IMP goodness=0.539624 rarity=0.5996 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Pathway_KEGG:hsa00100 Gene_EntrezGene:4047 -participates_in best=1 goodness=0.612798 rarity=0.766 relevance=0.8 reliability=1 source_db_name=KEGG source_db_version=51 Protein_UniProt:P48449 Gene_EntrezGene:4047 -codes_for best=1 goodness=0.9 rarity=1 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Gene_EntrezGene:51706 BiologicalProcess_GO:GO:0016126 participates_in best=1 evidence_code=IEA goodness=0.574715 rarity=0.6386 relevance=0.9 reliability=1 source_db_name=EntrezGene source_db_version=2009-09-01 Protein_UniProt:P04035 Protein_UniProt:P14324 functionally_associated_to best=0 goodness=0.350083 rarity=0.5557 relevance=0.9 reliability=0.7 source_db_name=STRING source_db_version=8.1 Protein_UniProt:P04035 Protein_UniProt:Q01581 functionally_associated_to best=1 goodness=0.505987 rarity=0.5737 relevance=0.9 reliability=0.98 source_db_name=STRING source_db_version=8.1 Protein_UniProt:P04035 Protein_UniProt:Q9UBM7 functionally_associated_to best=0 goodness=0.351583 rarity=0.5581 relevance=0.9 reliability=0.7 source_db_name=STRING source_db_version=8.1 Protein_UniProt:P14324 Protein_UniProt:Q15392 functionally_associated_to best=0 goodness=0.298533 rarity=0.5923 relevance=0.9 reliability=0.56 source_db_name=STRING source_db_version=8.1 Protein_UniProt:P14324 Protein_UniProt:Q9UBM7 functionally_associated_to best=0 goodness=0.328625 rarity=0.5796 relevance=0.9 reliability=0.63 source_db_name=STRING source_db_version=8.1 Protein_UniProt:P48449 Protein_UniProt:Q15392 functionally_associated_to best=0 goodness=0.470213 rarity=0.587 relevance=0.9 reliability=0.89 source_db_name=STRING source_db_version=8.1 Protein_UniProt:P48449 Protein_UniProt:Q9UKR5 functionally_associated_to best=0 goodness=0.319567 rarity=0.6575 relevance=0.9 reliability=0.54 source_db_name=STRING source_db_version=8.1 BiologicalProcess_GO:GO:0010142 Protein_UniProt:P51639 -participates_in best=0 evidence_code=TAS goodness=0.83973 rarity=0.933 relevance=0.9 reliability=1 source_db_name=SwissProt source_db_version=57.6 ActiveSite_InterPro:IPR000590 Protein_UniProt:Q01581 -contains best=0 goodness=0.592908 rarity=0.7411 relevance=0.8 reliability=1 source_db_name=SwissProt source_db_version=57.6 Protein_UniProt:Q01581 Family_InterPro:IPR010122 belongs_to best=0 goodness=0.584679 rarity=0.7308 relevance=0.8 reliability=1 source_db_name=SwissProt source_db_version=57.6 Pathway_UniProt/pathway:1138 Protein_UniProt:Q15392 -participates_in best=0 goodness=0.655776 rarity=0.8197 relevance=0.8 reliability=1 source_db_name=UniProt source_db_version=15.6 Protein_UniProt:Q15392 Protein_UniProt:P48449 functionally_associated_to best=1 Protein_UniProt:Q15392 Protein_UniProt:Q9UBM7 functionally_associated_to best=0 goodness=0.513964 rarity=0.5949 relevance=0.9 reliability=0.96 source_db_name=STRING source_db_version=8.1 Protein_UniProt:Q9UBM7 Pathway_UniProt/pathway:1138 participates_in best=0 goodness=0.655776 rarity=0.8197 relevance=0.8 reliability=1 source_db_name=UniProt source_db_version=15.6 Protein_UniProt:Q9UBM7 Protein_UniProt:Q15392 functionally_associated_to best=1 Protein_UniProt:Q9UKR5 Protein_UniProt:P48449 functionally_associated_to best=1 # _attributes ActiveSite_InterPro:IPR000590 PrimaryName=Hydroxymethylglutaryl-coenzyme+A+synthase,+active+site ShortName=HMG_CoA_synt_AS best=1 degree=25 distance=2 distance_bestpath=2 goodness=0.631123 goodness_of_best_path=0.307035 label=HMG_CoA_synt_AS len_of_best_path=4 pinned=0 pos=422.4,586.5 # _attributes BiologicalProcess_GO:GO:0006695 PrimaryName=cholesterol+biosynthetic+process ShortName=cholesterol+a. best=1 degree=205 distance=1 distance_bestpath=1 goodness=0.539624 goodness_of_best_path=0.291194 label=cholesterol+b. len_of_best_path=2 pinned=0 pos=1408.5,867.0 # _attributes BiologicalProcess_GO:GO:0008299 PrimaryName=isoprenoid+biosynthetic+process ShortName=isoprenoid+anabolism best=1 degree=201 distance=1 distance_bestpath=3 goodness=0.568011 goodness_of_best_path=0.307035 label=isoprenoid+b. len_of_best_path=4 pinned=0 pos=1105.0,587.4 # _attributes BiologicalProcess_GO:GO:0010142 PrimaryName=farnesyl+diphosphate+biosynthetic+process,+mevalonate+pathway ShortName=Ac-MVA+pathway best=0 degree=4 distance=3 distance_bestpath=3 goodness=0.52634 goodness_of_best_path=0.243368 label=farnesyl+diphosphate+b. len_of_best_path=6 pinned=0 pos=1267.3,21.2 # _attributes BiologicalProcess_GO:GO:0016126 ShortName=sterol+anabolism best=1 degree=73 distance=1 distance_bestpath=1 goodness=0.574715 goodness_of_best_path=0.330297 label=sterol+biosynthetic+process len_of_best_path=2 pinned=0 pos=2578.0,1866.6 # _attributes BiologicalProcess_GO:GO:0045337 PrimaryName=farnesyl+diphosphate+biosynthetic+process ShortName=farnesyl+diphosphate+anabolism best=0 degree=4 distance=2 distance_bestpath=2 goodness=0.577974 goodness_of_best_path=0.243368 label=farnesyl+diphosphate+b. len_of_best_path=6 pinned=0 pos=803.2,156.4 # _attributes Drug_KEGG:D00359 ShortName=MK-803 best=0 degree=6 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Lovastatin len_of_best_path=3 pinned=0 pos=2342.6,868.7 # _attributes Drug_KEGG:D00434 ShortName=MK-733 best=0 degree=6 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Simvastatin len_of_best_path=3 pinned=0 pos=2443.8,608.6 # _attributes Drug_KEGG:D00887 ShortName=Lipitor best=0 degree=5 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Atorvastatin+calcium len_of_best_path=3 pinned=0 pos=1982.2,895.9 # _attributes Drug_KEGG:D00889 ShortName=Baycol best=0 degree=5 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Cerivastatin+sodium len_of_best_path=3 pinned=0 pos=1609.9,575.4 # _attributes Drug_KEGG:D00892 ShortName=Lescol best=0 degree=5 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Fluvastatin+sodium len_of_best_path=3 pinned=0 pos=1667.7,838.9 # _attributes Drug_KEGG:D00893 ShortName=CS-514 best=0 degree=5 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Pravastatin+sodium len_of_best_path=3 pinned=0 pos=2017.0,527.0 # _attributes Drug_KEGG:D01862 ShortName=NK+104 best=1 degree=5 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Pitavastatin+calcium len_of_best_path=3 pinned=0 pos=1821.5,521.0 # _attributes Drug_KEGG:D01915 ShortName=ZD+4522 best=0 degree=5 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Rosuvastatin+calcium len_of_best_path=3 pinned=0 pos=2316.2,759.9 # _attributes Drug_KEGG:D02258 ShortName=Lipitor best=0 degree=5 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Atorvastatin+calcium+hydrate len_of_best_path=3 pinned=0 pos=2462.4,804.9 # _attributes Drug_KEGG:D03601 ShortName=C14H23NO3 best=0 degree=4 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Crilvastatin len_of_best_path=3 pinned=0 pos=2191.3,897.6 # _attributes Drug_KEGG:D03643 ShortName=C24H31FO3 best=0 degree=4 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Dalvastatin len_of_best_path=3 pinned=0 pos=2287.3,562.7 # _attributes Drug_KEGG:D03816 ShortName=(C25H39O6)2.+Ca best=0 degree=4 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Tenivastatin+calcium len_of_best_path=3 pinned=0 pos=2498.2,706.4 # _attributes Drug_KEGG:D07474 ShortName=Sortis best=0 degree=4 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Atorvastatin len_of_best_path=3 pinned=0 pos=1526.6,691.0 # _attributes Drug_KEGG:D08410 ShortName=C23H36O7 best=0 degree=3 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Pravastatin len_of_best_path=3 pinned=0 pos=2185.3,508.3 # _attributes Drug_KEGG:D08492 ShortName=Creston best=0 degree=3 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.393895 label=Rosuvastatin len_of_best_path=3 pinned=0 pos=2290.8,657.0 # _attributes Enzyme_EC:1.1.1.34 ShortName=3-hydroxy-3-methylglutaryl-CoA+reductase best=0 degree=30 distance=1 distance_bestpath=2 goodness=0.694476 goodness_of_best_path=0.244036 label=hydroxymethylglutaryl-CoA+reductase len_of_best_path=5 pinned=0 pos=1470.5,471.8 # _attributes Family_InterPro:IPR010122 PrimaryName=Hydroxymethylglutaryl-CoA+synthase,+eukaryotic ShortName=HMG_CoA_synthase_euk best=0 degree=29 distance=2 distance_bestpath=2 goodness=0.631123 goodness_of_best_path=0.248698 label=HMG_CoA_synthase_euk len_of_best_path=6 pinned=0 pos=538.9,504.1 # _attributes Gene_EntrezGene:11161 OrganismId=9606 PrimaryName=chromosome+14+open+reading+frame+1 ShortName=C14orf1 best=1 degree=81 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.330297 label=C14orf1 len_of_best_path=2 organism=hsa pos=2294.2,1685.5 queryname=Gene_EntrezGene:11161 queryset=start fill=255/0/0 logFC=logFC:-0.993570 # _attributes Gene_EntrezGene:1717 OrganismId=9606 PrimaryName=7-dehydrocholesterol+reductase ShortName=DHCR7 best=1 degree=114 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.416311 label=DHCR7 len_of_best_path=3 organism=hsa pos=1538.5,987.7 queryname=Gene_EntrezGene:1717 queryset=start fill=255/0/0 logFC=logFC:-0.812285 # _attributes Gene_EntrezGene:1718 OrganismId=9606 PrimaryName=24-dehydrocholesterol+reductase ShortName=DHCR24 best=1 degree=66 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.416311 label=DHCR24 len_of_best_path=3 organism=hsa pos=1718.7,1026.8 queryname=Gene_EntrezGene:1718 queryset=start fill=255/0/0 logFC=logFC:-0.674278 # _attributes Gene_EntrezGene:2224 OrganismId=9606 PrimaryName=farnesyl+diphosphate+synthase+(farnesyl+pyrophosphate+synthetase,+dimethylallyltranstransferase,+geranyltranstransferase) ShortName=FDPS best=1 degree=58 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.393895 label=FDPS len_of_best_path=3 organism=hsa pos=1189.1,706.4 queryname=Gene_EntrezGene:2224 queryset=start fill=255/0/0 logFC=logFC:-0.577226 # _attributes Gene_EntrezGene:25675 OrganismId=10116 PrimaryName=3-hydroxy-3-methylglutaryl-Coenzyme+A+reductase ShortName=Hmgcr best=0 degree=46 distance=1 distance_bestpath=1 goodness=0.69644 goodness_of_best_path=0.243368 label=Hmgcr len_of_best_path=6 organism=rno pinned=0 pos=1865.8,373.1 # _attributes Gene_EntrezGene:3156 OrganismId=9606 PrimaryName=3-hydroxy-3-methylglutaryl-Coenzyme+A+reductase ShortName=HMGCR best=1 degree=117 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.409849 label=HMGCR len_of_best_path=3 organism=hsa pos=1846.2,675.8 queryname=Gene_EntrezGene:3156 queryset=start fill=255/0/0 logFC=logFC:-0.381084 # _attributes Gene_EntrezGene:3157 OrganismId=9606 PrimaryName=3-hydroxy-3-methylglutaryl-Coenzyme+A+synthase+1+(soluble) ShortName=HMGCS1 best=1 degree=47 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.409849 label=HMGCS1 len_of_best_path=3 organism=hsa pos=748.9,810.0 queryname=Gene_EntrezGene:3157 queryset=start fill=255/0/0 logFC=logFC:-0.750856 # _attributes Gene_EntrezGene:36209 OrganismId=7227 PrimaryName=Farnesyl+pyrophosphate+synthase ShortName=Fpps best=0 degree=42 distance=1 distance_bestpath=1 goodness=0.716767 goodness_of_best_path=0.243368 label=Fpps len_of_best_path=6 organism=dme pinned=0 pos=914.6,408.0 # _attributes Gene_EntrezGene:4047 OrganismId=9606 PrimaryName=lanosterol+synthase+(2,3-oxidosqualene-lanosterol+cyclase) ShortName=LSS best=1 degree=43 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.393895 label=LSS len_of_best_path=3 organism=hsa pos=1989.0,1046.3 queryname=Gene_EntrezGene:4047 queryset=start fill=255/0/0 logFC=logFC:-1.053002 # _attributes Gene_EntrezGene:51706 OrganismId=9606 PrimaryName=cytochrome+b5+reductase+1 ShortName=CYB5R1 best=1 degree=28 distance=0 distance_bestpath=0 goodness=1 goodness_of_best_path=0.330297 label=CYB5R1 len_of_best_path=2 organism=hsa pos=2901.0,2033.2 queryname=Gene_EntrezGene:51706 queryset=start fill=255/0/0 logFC=logFC:-1.848839 # _attributes MolecularFunction_GO:GO:0004421 PrimaryName=hydroxymethylglutaryl-CoA+synthase+activity ShortName=HMG-CoA+synthase+a. best=1 degree=35 distance=1 distance_bestpath=1 goodness=0.701248 goodness_of_best_path=0.307035 label=hydroxymethylglutaryl-CoA+s. len_of_best_path=4 pinned=0 pos=127.5,728.4 # _attributes Pathway_KEGG:hsa00100 OrganismId=9606 best=1 degree=47 distance=1 distance_bestpath=2 goodness=0.642781 goodness_of_best_path=0.393895 label=Biosynthesis+of+steroids len_of_best_path=3 organism=hsa pinned=0 pos=1927.0,764.1 # _attributes Pathway_UniProt/pathway:1138 PrimaryName=Steroid+biosynthesis;+cholesterol+biosynthesis best=0 degree=12 distance=2 distance_bestpath=2 goodness=0.590198 goodness_of_best_path=0.348334 label=Steroid+b...+biosynthesis len_of_best_path=4 pinned=0 pos=810.9,1264.8 # _attributes Protein_UniProt:P04035 OrganismId=9606 PrimaryName=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase ShortName=HMDH_HUMAN best=1 degree=548 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.409849 label=HMDH_HUMAN len_of_best_path=3 organism=hsa pinned=0 pos=1206.1,765.9 # _attributes Protein_UniProt:P14324 OrganismId=9606 PrimaryName=Farnesyl+pyrophosphate+synthetase ShortName=FPPS_HUMAN best=0 degree=273 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.319055 label=FPPS_HUMAN len_of_best_path=5 organism=hsa pinned=0 pos=914.6,948.6 # _attributes Protein_UniProt:P48449 OrganismId=9606 PrimaryName=Lanosterol+synthase ShortName=ERG7_HUMAN best=1 degree=312 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.380873 label=ERG7_HUMAN len_of_best_path=3 organism=hsa pinned=0 pos=1816.5,1284.3 # _attributes Protein_UniProt:P51639 OrganismId=10116 PrimaryName=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase ShortName=HMDH_RAT best=0 degree=167 distance=2 distance_bestpath=2 goodness=0.626796 goodness_of_best_path=0.243368 label=HMDH_RAT len_of_best_path=6 organism=rno pinned=0 pos=1592.0,203.2 # _attributes Protein_UniProt:Q01581 OrganismId=9606 PrimaryName=Hydroxymethylglutaryl-CoA+synthase,+cytoplasmic ShortName=HMCS1_HUMAN best=1 degree=153 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.409849 label=HMCS1_HUMAN len_of_best_path=3 organism=hsa pinned=0 pos=578.0,709.8 # _attributes Protein_UniProt:Q15392 OrganismId=9606 PrimaryName=24-dehydrocholesterol+reductase ShortName=DHC24_HUMAN best=1 degree=196 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.416311 label=DHC24_HUMAN len_of_best_path=3 organism=hsa pinned=0 pos=1292.8,1187.5 # _attributes Protein_UniProt:Q9UBM7 OrganismId=9606 PrimaryName=7-dehydrocholesterol+reductase ShortName=DHCR7_HUMAN best=1 degree=261 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.416311 label=DHCR7_HUMAN len_of_best_path=3 organism=hsa pinned=0 pos=1024.2,1055.7 # _attributes Protein_UniProt:Q9UKR5 OrganismId=9606 PrimaryName=Probable+ergosterol+biosynthetic+protein+28 ShortName=ERG28_HUMAN best=1 degree=34 distance=1 distance_bestpath=1 goodness=0.9 goodness_of_best_path=0.25885 label=ERG28_HUMAN len_of_best_path=3 organism=hsa pinned=0 pos=2046.0,1492.6